KMID : 1035120130130040210
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Asian Oncology Nursing 2013 Volume.13 No. 4 p.210 ~ p.221
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A Study on Vascular Pain Due to Gemcitabine and According to Clinical Factors
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Seong So-Ryoung
Lee Nam-Ju Lee Mi-Jin Jang Hyun-Ah Song Min-Ju Park Se-Jung Kim Jee-Yoon Ryoo Baek-Yeol
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Abstract
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Purpose: This study was performed to examine vascular pain due to gemcitabine and according to clinical factors.
Methods: The survey was performed with 525 cancer patients visiting chemotherapy infusion room in one general hospital. The data were collected via self-reported questionnaire, researchers observation, and reviewing medical records. Data were analyzed descriptive statistics, ttest, Kruskal-Wallis test, Tukey test using ranks, Jonckheere-Terpstra test, and Spearman correlation analysis were used.
Results: The mean scores of the intensity and onset time of vascular pain were 3.06¡¾2.16 and 8.13¡¾13.13 min, and each other were negative correlaton. Degree of intensity of vascular pain had a significant difference on gender (p=.003), age (p=.004), weight (p=.019), Body mass index (BMI) (p=.005), Body surface area (BSA) (p=.030), infusion time (p<.001), dose (p=.027), dose per minute (p<.001), the number of administered gemcitabine (p=.005), combination chemotherapeutic drug (p=.013) and tumor type (p=.002). Degree of onset time of vascular pain had a significant difference on infusion time (p=.044), combination chemotherapy (p=.001) and injection site (p=.001).
Conclusion: Patients administrated gemcitabine were experiencing various vascular pain, and vascular pain had a difference on clinical factors. Therefore, oncology nurses should be considered significant clinical factors to implement effective interventions to patients administered gemcitabine.
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KEYWORD
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Gemcitabine, Vascular, Pain, Neoplasms
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